Up to 8 players compete to be the first to travel through the nephron from glomerulus to collecting duct. Players progress through the nephron by correctly answering questions related to the section of the nephron their playing piece is currently in. Land on an ADH square and answer a question about role of ADH in renal function.

The game includes 6 card packs allowing players to explore what happens in each part of the nephron:

• Glomerulus
• Proximal Tubule
• Loop of Henle
• Distal Tubule
• Collecting Duct
• Antidiuretic Hormone (ADH)